Time sensitive managements in hepato-gastroenterology

doi:10.4254/wjh.v18.i4.114793

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Apr 27, 2026; 18(4): 114793
Published online Apr 27, 2026. doi: 10.4254/wjh.v18.i4.114793

Table 2 Postexposure prophylaxis in health care personnel

HCP vaccination status	HCP immune testing (HBsAb titre)	Source status (HBsAg) testing	Postexposure prophylaxis (PEP)		PEP protection testing (HBsAb titre)
HCP vaccination status	HCP immune testing (HBsAb titre)	Source status (HBsAg) testing	Vaccination	HBIG	PEP protection testing (HBsAb titre)
Documented responder after CVCS	Not indicated	Not indicated	Not indicated	Not indicated	Not indicated
Documented non-responder after 2 CVCS	Anti-HBs < 10 IU/L	Negative	Not indicated	Not indicated	Not indicated
Documented non-responder after 2 CVCS	Anti-HBs < 10 IU/L	Positive/unknown	Not indicated	Of 2 doses one month apart	Not indicated
Response not tested after CVCS	Anti-HBs ≥ 10 IU/L	Not indicated	Not indicated	Not indicated	Not indicated
	Anti-HBs < 10 IU/L	Negative	Re-vaccinate	Not indicated	Yes
	Anti-HBs < 10 IU/L	Positive/unknown	Start CVCS	One dose ASAP up to 7 days	Yes
Unvaccinated/incomplete VCS	Anti-HBs ≥ 10 IU/L (post infection recovery)	Not indicated	Not indicated	Not indicated	Not indicated
	Anti-HBs < 10 IU/L	Negative	Start CVCS	Not indicated	Yes
	Anti-HBs < 10 IU/L	Positive/unknown	Start CVCS	One dose ASAP up to 7 days	Yes

HCP: Health care personnel; HBsAb: Hepatitis B surface antibody; HBsAg: Hepatitis B surface antigen; PEP: Post-exposure prophylaxis; HBIG: Hepatitis B immune globulin; CVCS: Complete vaccination course series; VCS: Vaccination course series; ASAP: As soon as possible.

Full Size Table

Citation: Said EM, Soliman HH, Gabal HMR, Emara MH, Fouad Y, Elzahaby A, Anees M, Zaky S, Sakr MA. Time sensitive managements in hepato-gastroenterology. World J Hepatol 2026; 18(4): 114793
URL: https://www.wjgnet.com/1948-5182/full/v18/i4/114793.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i4.114793

Said EM, Soliman HH, Gabal HMR, Emara MH, Fouad Y, Elzahaby A, Anees M, Zaky S, Sakr MA. Time sensitive managements in hepato-gastroenterology. World J Hepatol 2026; 18(4): 114793 [DOI: 10.4254/wjh.v18.i4.114793]

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