Overexpression and clinicopathological significance of cullin-2 in hepatocellular carcinoma progression

doi:10.4254/wjh.v18.i3.117134

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Mar 27, 2026; 18(3): 117134
Published online Mar 27, 2026. doi: 10.4254/wjh.v18.i3.117134

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Figure 9 Analysis of potential molecular mechanisms of Cullin-2 in hepatocellular carcinoma. A: This study identified 190 hepatocellular carcinoma highly expressed Cullin-2 (CUL2)-positively correlated genes; B: The CUL2 co-expression gene regulatory network is closely related to Gene Ontology terms such as nuclear division, chromosome segregation, and mitotic cell cycle transition, and significantly enriched in signaling pathways including nucleocytoplasmic transport and cell cycle. HCC: Hepatocellular carcinoma; SMD: Standardized mean difference.

Citation: Tang P, Nong QH, Xiong KH, Tang HH, Huang BB, Huang GL, Li Q, He SP, Chen G, Feng ZB, Li JD. Overexpression and clinicopathological significance of cullin-2 in hepatocellular carcinoma progression. World J Hepatol 2026; 18(3): 117134
URL: https://www.wjgnet.com/1948-5182/full/v18/i3/117134.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i3.117134

Tang P, Nong QH, Xiong KH, Tang HH, Huang BB, Huang GL, Li Q, He SP, Chen G, Feng ZB, Li JD. Overexpression and clinicopathological significance of cullin-2 in hepatocellular carcinoma progression. World J Hepatol 2026; 18(3): 117134 [DOI: 10.4254/wjh.v18.i3.117134]

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