Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients

Table 7 Relationship between oesophageal varices grades and different parameters in group I and group II (including post hoc analysis)

Parameter	Group I			Group II
	F value	P value	Significant pairs (Scheffe test)	F value	P value	Significant pairs (Scheffe test)
TSH (μU/mL)	1.16	0.35	NS	1.76	0.18	NS
FT3 (pmol/L)	7.96	0.001	Grade 1 vs 3, grade 2 vs 3, grade 3 vs 4 (P < 0.05)	4.55	0.01	Grade 0 vs 3, grade 1 vs 3 (P < 0.05)
FT4 (pmol/L)	1.62	0.21	NS	1.32	0.29	NS
PLT (× 103/μL)	3.96	0.02	Grade 1 vs 3 (P < 0.05)	7.60	0.00	Grade 0 vs 3, grade 1 vs 3 (P < 0.05)
INR	3.52	0.03	Grade 2 vs 4 (P < 0.05)	6.88	0.00	Grade 1 vs 4, grade 2 vs 4 (P < 0.05)
Spleen size (cm)	3.31	0.04	Grade 1 vs 3 (P < 0.05)	6.58	0.00	Grade 0 vs 3, grade 1 vs 3 (P < 0.05)
PVD (mm)	3.64	0.02	Grade 1 vs 4 (P < 0.05)	8.40	0.00	Grade 0 vs 3, grade 1 vs 3 (P < 0.05)

Analysis of variance of clinical parameters across esophageal variceal grades within group I and group II. The P-value represents the overall significance of the difference across all grades. Significant differences between specific grade pairs were determined using the Scheffe post-hoc test. NS: Not significant; PLT: Platelet count; INR: International normalized ratio; TSH: Thyroid-stimulating hormone; FT3: Free triiodothyronine; FT4: Free thyroxine; PVD: Portal vein diameter.