Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients

doi:10.4254/wjh.v18.i3.117040

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Mar 27, 2026; 18(3): 117040
Published online Mar 27, 2026. doi: 10.4254/wjh.v18.i3.117040

Table 1 Demographic and clinical characteristics of the study groups, n (%)/mean ± SD

Parameter	Group I (n = 31)	Group II (n = 31)	Group III (n = 31)	P value¹
Age (years)	57 ± 9.46	60 ± 6.59	56 ± 6.52	0.06
FIB-4 index	4.5 ± 1.2	4.3 ± 1.1	NA	0.48
APRI score	2.1 ± 0.7	1.9 ± 0.6	NA	0.25
Sex (male/female)	22/9	19/12	14/17	0.08
Child-Pugh score				< 0.001
Class A	7 (22.6)	9 (29.1)
Class B	18 (58.0)	17 (54.8)
Class C	6 (19.4)	5 (16.1)

¹Comparisons were performed using one-way analysis of variance for continuous variables and the χ² test for categorical variables.

FIB-4: Fibrosis-4; APRI: Aspartate aminotransferase to platelet ratio index; NA: Not available.

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Citation: Othman AAA, Elsharkawy L, Saleh MW, Mohamed MM, Elsayed FMA. Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients. World J Hepatol 2026; 18(3): 117040
URL: https://www.wjgnet.com/1948-5182/full/v18/i3/117040.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i3.117040

Othman AAA, Elsharkawy L, Saleh MW, Mohamed MM, Elsayed FMA. Multimarker model for non-invasive assessment of variceal bleeding in chronic hepatitis C cirrhotic patients. World J Hepatol 2026; 18(3): 117040 [DOI: 10.4254/wjh.v18.i3.117040]

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