Some peculiarities in the abnormal course of hepatitis A in childhood

Table 2 Comparisons of clinical and laboratory findings in patients with typical and atypical course of hepatitis A, n (%)

Parameter	Typical	Atypical	P value
Clinical manifestation	85 (73.9)	30 (26)	N/A
Mean age (years)	4.15	8.28	0.002
Males	42 (49.41)	16 (53.33)	N/A
Average length of hospitalization (days)	5.14 (3-7)	8.64 (5-18)	0.005
Fever	46 (54.11)	27 (90)	0.002
Nausea/vomiting	51 (60.0)	25 (83.33)	0.001
Pruritus	32 (37.64)	23 (76.66)	0.03
Аbdominal pain	40 (47.05)	17 (56.66)	NS
Diarrhea	13 (15.29)	8 (26.66)	0.02
Headache	28 (32.94)	15 (50)	0.005
AST (IU/L), peak level	1250	1640	0.01
ALT (IU/L), peak level	1035	2268	0.02
Bilirubin (mg/dL), peak level	3.4	8.9	0.02
WBCs (103/mm3), initial level	6.7	13.9	0.007
Hemoglobin (g/dL), initial level	11.4	8.9	NS
Platelet (103/mm3), initial level	155	148	NS

WBC: White blood cell; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; N/A: Not applicable; NS: Not significant.