Some peculiarities in the abnormal course of hepatitis A in childhood

Table 1 Clinical and laboratory characteristics in patients with hepatitis A (n = 115)

	Symptoms	n (%)
Clinical features of hepatitis A	Interval from symptom onset to hospital admission (days)	5.5 (2-9)
	Average length of hospitalization (days)	6.86 (5-18)
	Аverage time of pre icteric period (days)	4.3 (1-7)
Presenting symptoms (%)	General weakness	72
	Fever	52
	Jaundice	98
	Nausea/vomiting	73
	Аbdominal pain	44
	Diarrhea	18
Laboratory parameters	AST (IU/L), initial/peak level (normal range)	910/1350 (< 40)
	ALT (IU/L), initial/peak level (normal range)	1020/1410 (< 40)
	Bilirubin (mg/dL), initial/peak level (normal range)	3.4/6.8 (0.2-1.2)
	WBC (103/mm3), initial level (normal range)	6.1 (4-10)
	Hemoglobin (g/dL), initial level (normal range)	12.5 (12-16)
	Platelet (103/mm3), initial level (normal range)	166 (130-360)
Clinical outcomes	Typical course/recovery without complications	85 (73.91)
	Prolonged icteric period	11 (9.56)
	Acute acalculous cholecystitis	15 (13.04)
	Ascites	2 (1.73)
	Fulminant hepatitis, spontaneous recovery	1 (0.86)
	Thrombocytopenia	1 (0.86)

WBC: White blood cell; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.