Transjugular intrahepatic portosystemic shunt improves survival in anticoagulation-resistant hepatic sinusoidal obstructive syndrome patients: A multicenter retrospective study

Table 2 Univariate and multivariate Cox regression, hazard ratio (95%CI)

	Univariate analysis	P value	Multivariate analysis	P value
Age	1.063 (0.995-1.136)	0.068	1.067 (1.000-1.137)	0.049
Sex	0.588 (0.169-2.046)	0.403
Treatment (transjugular intrahepatic portosystemic shunts/anticoagulation therapy)	0.428 (0.165-1.111)	0.081	0.321 (0.116-0.886)	0.028
White blood cells	1.091 (0.959-1.242)	0.187
Hemoglobin	1.033 (1.000-1.067)	0.052
Platelets	0.992 (0.978-1.005)	0.225
Total bilirubin	1.286 (1.115-1.483)	0.001	1.211 (1.035-1.418)	0.017
Direct bilirubin	1.372 (1.119-1.682)	0.002
AST	1.007 (1.002-1.012)	0.009	1.007 (1.001-1.014)	0.028
ALT	1.008 (1.001-1.015)	0.020
ALT/AST	0.323 (0.035-3.002)	0.320
Alkaline phosphatase	0.999 (0.993-1.005)	0.813
Gamma-glutamyl transferase	0.998 (0.991-1.004)	0.483
Albumin	1.011 (0.878-1.164)	0.881
Cholinesterase	0.437 (0.216-0.883)	0.021	0.524 (0.218-1.260)	0.149
Blood urea nitrogen	1.046 (0.942-1.160)	0.400
Serum creatinine	1.004 (0.997-1.011)	0.282
Fibrinogen	0.638 (0.274-1.483)	0.297
Portal vein velocity	1.011 (0.922-1.110)	0.811

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.