Adipokine profiles reflect metabolic dysfunction but not fibrosis in patients with primary biliary cholangitis

Table 1 Diagnostic criteria for metabolic syndrome based on the International Diabetes Federation definition

Component	Diagnostic criterion
Central obesity (mandatory)	Waist circumference above the ethnicity-specific threshold1
Plus at least two of the following
Elevated TG	≥ 150 mg/dL (1.70 mmol/L) or specific treatment for this lipid abnormality
Reduced HDL-C	< 40 mg/dL (< 1.03 mmol/L) in men; < 50 mg/dL (< 1.29 mmol/L) in women, or specific treatment
Elevated blood pressure	Systolic ≥ 130 mmHg or diastolic ≥ 85 mmHg, or treatment of previously diagnosed hypertension
Elevated fasting glucose	≥ 100 mg/dL (5.60 mmol/L) or previously diagnosed type 2 diabetes

¹Ethnic-specific values for waist circumference should be applied (e.g., > 94 cm for men and > 80 cm for women of European origin).

TG: Triglycerides; HDL-C: High-density lipoprotein cholesterol.