Predictive tool for evident histological liver injury in chronic hepatitis B patients: Development and validation

Table 2 Univariable and multivariable logistic regression model for predicting development of evident histological liver injury in patients with chronic hepatitis B

Factor	Univariable analysis			Multivariable analysis
	OR	95%CI	P value	OR	95%CI	P value
Male	0.34	0.16-0.73	0.006
Age, year	2.04	1.43-2.92	< 0.001
L59	0.07	0.03-0.15	< 0.001	0.15	0.06-0.38	< 0.001
PLT, × 109/L	2.24	1.37-3.66	0.001	2.71	1.09-6.75	0.03
ALT, U/L	1.79	1.02-3.18	0.048	7.20	1.35-28.8	0.02
AST, U/L	5.56	2.14-14.47	< 0.001	8.40	1.10-63.8	0.04
ALB, g/L	5.69	1.23-26.33	0.026
TBIL, μmol/L	2.31	1.33-4.02	0.003
DBIL, μmol/L	3.54	1.79-6.99	< 0.001

OR: Odds ratio; CI: Confidence interval; PLT: Platelet; ALT: Alanine transaminase; AST: Aspartate transaminase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin.