Dynamic immune response and its influencing factors in COVID-19 patients with non-alcoholic fatty liver disease: A cohort study

doi:10.4254/wjh.v18.i2.113004

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Hepatol. Feb 27, 2026; 18(2): 113004
Published online Feb 27, 2026. doi: 10.4254/wjh.v18.i2.113004

Table 2 Comparison of lymphocyte subsets and their percentages between obese patients without non-alcoholic fatty liver disease and those with non-alcoholic fatty liver disease, mean ± SD

Variable	Obese patients without NAFLD	Obese patients with NAFLD	P value
LY (cells/μL)	2023.96 ± 790.22	2306.34 ± 946.34	0.117
LY%	21.01 ± 7.14	21.67 ± 7.90	0.377
CD3+ (cells/μL)	1455.32 ± 584.53	1654.04 ± 693.65	0.097
CD3+CD4+ (cells/μL)	842.29 ± 385.28	977.5 ± 436.20	0.064
CD3+CD8+ (cells/μL)	515.00 ± 251.28	585.37 ± 312.55	0.475
CD3+%	72.38 ± 6.71	71.98 ± 7.15	0.939
CD3+CD4+%	41.56 ± 7.26	41.94 ± 7.37	0.550
CD3+CD8+%	27.12 ± 10.30	25.45 ± 7.43	0.067
CD4/CD8	1.81 ± 0.75	1.82 ± 0.74	0.759
CD19+ (cells/μL)	252.04 ± 238.43	361.28 ± 245.29	0.311
CD56+ (cells/μL)	276.14 ± 169.13	237.26 ± 170.36	0.788
CD19+%	10.61 ± 4.51	15.02 ± 6.40	0.019
CD56+%	13.77 ± 8.25	10.49 ± 6.79	0.249

NAFLD: Non-alcoholic fatty liver disease; LY: Lymphocyte counts.

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Citation: Yan P, Li R, Yuan XY, Wang Y, Lan LJ, Yu XP, Liu DF. Dynamic immune response and its influencing factors in COVID-19 patients with non-alcoholic fatty liver disease: A cohort study. World J Hepatol 2026; 18(2): 113004
URL: https://www.wjgnet.com/1948-5182/full/v18/i2/113004.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i2.113004

Yan P, Li R, Yuan XY, Wang Y, Lan LJ, Yu XP, Liu DF. Dynamic immune response and its influencing factors in COVID-19 patients with non-alcoholic fatty liver disease: A cohort study. World J Hepatol 2026; 18(2): 113004 [PMID: 41809480 DOI: 10.4254/wjh.v18.i2.113004]

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