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Observational Study
©The Author(s) 2026.
World J Hepatol. Feb 27, 2026; 18(2): 111962
Published online Feb 27, 2026. doi: 10.4254/wjh.v18.i2.111962
Table 4 Odds ratios and interaction effects between clinical scores and metabolic syndrome for predicting steatosis and metabolic dysfunction-associated liver disease
Score
Variable
OR
95%CI
P value
Any steatosis
NLFS Score 1.150.93-1.700.353
MetS0.880.31-2.410.809
Score-MetS interaction1.240.78-1.850.295
HSIScore 0.990.09-1.200.896
MetS< 0.01< 0.01- > 1000.904
Score-MetS interaction1.000.80-1.240.966
FLIScore 0.750.420.239
MetS< 0.01< 0.01- > 1000.462
Score-MetS interaction1.290.67-2.660.452
Moderate-to-severe steatosis
NLFSScore0.930.40-1.220.780
MetS1.850.38-13.630.479
Score-MetS interaction1.350.95-3.250.266
HSIScore 0.870.54-1.280.518
MetS< 0.01< 0.01- > 1000.400
Score-MetS interaction1.220.82-2.000.354
FLIScore 1.630.66-10.990.471
MetS< 0.01< 0.01- > 1000.718
Score-MetS interaction1.340.18-4.840.710
MASH
NLFS Score 1.060.87-1.220.478
MetS0.770.20-3.250.715
Score-MetS interaction1.140.90-1.480.279
HSIScore 0.930.069-1.200.584
MetS< 0.01< 0.01- > 1000.329
Score-MetS interaction0.150.87-1.560.325
FLIScore 1.170.71-2.930.589
MetS< 0.01< 0.01- > 1000.462
Score-MetS interaction1.450.48-3.840.463

  • Citation: Farina GS, Brambilla B, Pandolfo EM, Lazzaretti LKN, Kuiava SMS, Graciolli AM, Kriger VM, Fistarol CHDB, Sgarioni AC, Giovanardi HP, Tregnago AC, Riva F, Scholze CDS, Agostini DC, Dellamea B, Tamayo A, Cerqueira TL, Soldera J, Illigens BMW. Performance of three clinical scores for steatosis and steatohepatitis and their interaction with metabolic syndrome in obese individuals. World J Hepatol 2026; 18(2): 111962
  • URL: https://www.wjgnet.com/1948-5182/full/v18/i2/111962.htm
  • DOI: https://dx.doi.org/10.4254/wjh.v18.i2.111962

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