Autoimmune hepatitis in the context of systemic lupus erythematosus: A narrative review of overlap syndrome and lupus-associated hepatitis

doi:10.4254/wjh.124793

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Oct 27, 2026; 18(10): 124793
Published online Oct 27, 2026. doi: 10.4254/wjh.124793

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Figure 2 Proposed diagnostic algorithm for the evaluation of liver enzyme abnormalities in patients with systemic lupus erythematosus. SLE: Systemic lupus erythematosus; HBV: Hepatitis B virus; HCV: Hepatitis C virus; EBV: Epstein-Barr virus; CMV: Cytomegalovirus; VZV: Varicella-zoster virus; HSV: Herpes simplex virus; MASLD: Metabolic dysfunction-associated steatotic liver disease; ANA: Antinuclear antibody; dsDNA: Double-stranded DNA; ALT: Alanine aminotransferase; ULN: Upper limit of normal; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; AIH: Autoimmune hepatitis; IgG: Immunoglobulin G; SMA: Smooth muscle antibody; SLA: Soluble liver antigen; LP: Liver-pancreas; IAIHG: International Autoimmune Hepatitis Group.

Citation: Elghezewi A, Mohamed M. Autoimmune hepatitis in the context of systemic lupus erythematosus: A narrative review of overlap syndrome and lupus-associated hepatitis. World J Hepatol 2026; 18(10): 124793
URL: https://www.wjgnet.com/1948-5182/full/v18/i10/124793.htm
DOI: https://dx.doi.org/10.4254/wjh.124793

Elghezewi A, Mohamed M. Autoimmune hepatitis in the context of systemic lupus erythematosus: A narrative review of overlap syndrome and lupus-associated hepatitis. World J Hepatol 2026; 18(10): 124793 [DOI: 10.4254/wjh.124793]

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