Risk factors and predictive model for hepatitis B virus deoxyribonucleic acid elevation in mid-to-late pregnancy with low viremia

Table 3 One-way logistic analysis of hepatitis B virus DNA elevation in mid- to late-term pregnancy

Factor	Β	SE	Wald	OR (95%CI)	P value
Parity	0.133	0.150	0.786	1.14 (0.85-1.53)	0.375
BMI (kg/m2)	0.014	0.034	0.174	1.01 (0.95-1.09)	0.677
Age	0.049	0.024	4.393	1.05 (1.00-1.10)	0.036
HBeAg positive	0.893	0.396	5.083	2.44 (1.12-5.30)	0.024
HBV DNA ≥ 100 IU/mL	1.547	0.216	51.139	4.70 (3.07-7.18)	< 0.001
TBA, µmol/L	0.027	0.037	0.508	1.03 (0.95-1.11)	0.476
TBIL, µmol/L	-0.008	0.031	0.060	0.99 (0.93-1.05)	0.807
DBIL, µmol/L	-0.023	0.098	0.057	0.98 (0.81-1.18)	0.812
IBIL, µmol/L	-0.022	0.033	0.423	0.98 (0.92-1.04)	0.515
AST ≥ 19 U/L	0.224	0.241	0.865	1.25 (0.78-2.01)	0.352
ALT ≥ 19 U/L	0.014	0.271	0.003	1.01 (0.60-1.73)	0.958
TP, g/L	0.034	0.056	0.359	1.03 (0.93-1.15)	0.549
ALB, g/L	-0.002	0.058	0.001	1.00 (0.89-1.12)	0.979
GLB, g/L	0.073	0.076	0.913	1.08 (0.93-1.25)	0.339
HGB, g/L	0.009	0.009	1.036	1.01 (0.99-1.03)	0.309
PLT, × 109/L	0.000	0.002	0.007	1.00 (0.99-1.01)	0.933
WBC, × 109/L	-0.036	0.054	0.445	0.96 (0.87-1.07)	0.505
TC, mmol/L	0.042	0.139	0.091	1.04 (0.79-1.37)	0.763
TG, mmol/L	-0.475	0.251	3.596	0.62 (0.38-1.02)	0.058
HDL-C, mmol/L	0.206	0.493	0.175	1.23 (0.47-3.23)	0.676
LDL-C, mmol/L	-0.047	0.147	0.102	0.95 (0.72-1.27)	0.750
HbA1c, %	-0.413	0.344	1.443	0.66 (0.34-1.30)	0.230
Cr, µmol/L	0.009	0.015	0.345	1.01 (0.98-1.04)	0.557
PT, seconds	0.097	0.111	0.773	1.10 (0.89-1.37)	0.379
APTT, seconds	-0.015	0.021	0.488	0.99 (0.95-1.03)	0.485
INR	2.882	2.072	1.934	17.85 (0.31-1036.05)	0.164

OR: Odds ratio; CI: Confidence interval; BMI: Body mass index; HBeAg: Hepatitis B virus e antigen; HBV DNA: Hepatitis B virus deoxyribonucleic acid; TBA: Total bile acid; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; TP: Total protein; ALB: Albumin; GLB: Globulin; HGB: Hemoglobin; PLT: Platelet; WBC: White blood cell; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; HbA1c: Glycated hemoglobin; Cr: Creatinine; PT: Prothrombin time; APTT: Activated partial thromboplastin time; INR: International normalized ratio.