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Copyright: ©Author(s) 2026.
World J Hepatol. Oct 27, 2026; 18(10): 123353
Published online Oct 27, 2026. doi: 10.4254/wjh.123353
Table 3 Studies of health-state utilities in liver disease
Ref.
n
Study design
Participants’ characteristics
Outcome
McLernon et al[24]30 studies from the United States, Canada, the United Kingdom, Germany, Australia, Italy, and the NetherlandsSystematic reviewInclusion criteria: English-language studies of any design that had: (1) Measured utility using health-state utility tools from liver disease patients, physicians, or adults with no liver disease; or (2) Estimated health-state utilities for various liver diseases from expert opinion. Exclusion criteria: (1) Letters, comments, news articles; (2) Studies unrelated to liver disease; (3) Utility estimates taken from the literature; (4) Insufficient information on how the utility was derived; and (5) Duplicate utilities from the same populationThe utility of compensated cirrhosis was 0.748
Levy et al[23]600 people (100 each from the United States, Canada, the United Kingdom, Spain, Hong Kong, and China)Descriptive (using an interviewer-administered survey)Demographics: Mean age: 41.5 years, female: 57.3%. Inclusion criteria: Age 18 years or older; Exclusion criteria: Inability to communicate in the official language(s) of the country, known cognitive impairment, or visible intoxicationIn China, the utilities of HCC, liver transplant, and post-liver transplant were 0.310, 0.540, and 0.683, respectively


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