Current management strategies for sarcopenia and frailty in cirrhosis: Missing link in transplant candidacy

doi:10.4254/wjh.v18.i1.115048

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jan 27, 2026; 18(1): 115048
Published online Jan 27, 2026. doi: 10.4254/wjh.v18.i1.115048

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Figure 2 Pathophysiology of sarcopenia in cirrhosis. Pathophysiological mechanisms linking cirrhosis to sarcopenia, including hyperammonemia, endotoxemia, cytokine release, and insulin resistance, all of which contribute to anabolic resistance, muscle mass loss, and functional decline. IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α.

Citation: Goyal MK, Chowdhary R, Vohra C, Patel M, Kalra S, Mehta M, McNulty R, Goyal K, Vuthaluru AR, Goyal O. Current management strategies for sarcopenia and frailty in cirrhosis: Missing link in transplant candidacy. World J Hepatol 2026; 18(1): 115048
URL: https://www.wjgnet.com/1948-5182/full/v18/i1/115048.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i1.115048

Goyal MK, Chowdhary R, Vohra C, Patel M, Kalra S, Mehta M, McNulty R, Goyal K, Vuthaluru AR, Goyal O. Current management strategies for sarcopenia and frailty in cirrhosis: Missing link in transplant candidacy. World J Hepatol 2026; 18(1): 115048 [PMID: 41640962 DOI: 10.4254/wjh.v18.i1.115048]

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