Enhanced surgical tolerance of schistosomiasis-induced fibrotic liver following treatment with Ziziphus plant extract

Table 2 Serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and bilirubin in different hamster groups, mean ± SD

	Control negative group I	Control negative ZSCLE-treated group II	Infected BLV group III	Infected BLV and ZSCLE-treated group IV	Infected BLZ, ZSCLE-treated, and 50% resected group V	P value
Serum ALT (U/L)	27.01 ± 2.86	29.01 ± 3.75	87.44 ± 2.62a,b	39.90 ± 2.62a,b,c	38.08 ± 2.09a,b,c	< 0.0001
Serum AST (U/L)	30.75 ± 1.07	31.58 ± 0.96	99.85 ± 2.17a,b	42.44 ± 1.96a,b,c	41.18 ± 2.10a,b,c	< 0.0001
Serum ALP (U/L)	65.69 ± 1.63	68.35 ± 1.99	144.41 ± 2.39a,b	79.72 ± 4.45a,b,c	77.45 ± 1.39a,b,c	< 0.0001
Serum bilirubin (mg/dL)	0.22 ± 0.03	0.26 ± 0.03	0.93 ± 0.05a,b	0.41 ± 0.03a,b,c	0.39 ± 0.05a,b,c	< 0.0001

^aP < 0.05 vs group I.

^bP < 0.05 vs group II.

^cP < 0.05 vs group III.

Statistical tests: One way ANOVA followed by post hoc Tukey’s multiple comparison test. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; BLV: Bovine leukemia virus; ZSCLE: Ziziphus spina-christi leaf extract.