Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction

doi:10.4254/wjh.v18.i1.114045

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Hepatol. Jan 27, 2026; 18(1): 114045
Published online Jan 27, 2026. doi: 10.4254/wjh.v18.i1.114045

Table 2 Sensitivity and specificity of each autoantibody in diagnosing autoimmune hepatitis

Autoantibody	Sensitivity	Specificity
ANA	83.7%	18.4%
SMA	18.6%	94.7%
Anti-LKM	7.0%	94.7%
Anti-LC-1	11.4%	93.8%
Anti-SLA/LP	14.0%	81.6%

ANA: Anti-nuclear antibodies; SMA: Smooth muscle antibodies; Anti-LKM: Anti-liver kidney microsomal antibodies; Anti-LC-1: Anti-liver cytosol type 1; Anti-SLA/LP: Antibodies against soluble liver antigen/Liver pancreas autoantigen.

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Citation: Ferreira AI, Costa Azevedo M, Macedo Silva V, Xavier S, Magalhães J, Cotter J. Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction. World J Hepatol 2026; 18(1): 114045
URL: https://www.wjgnet.com/1948-5182/full/v18/i1/114045.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i1.114045

Ferreira AI, Costa Azevedo M, Macedo Silva V, Xavier S, Magalhães J, Cotter J. Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction. World J Hepatol 2026; 18(1): 114045 [PMID: 41640969 DOI: 10.4254/wjh.v18.i1.114045]

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