Clinical spectrum and genotype-phenotype correlation of ABCB4 mutations in children: Insights from a North Indian cohort

doi:10.4254/wjh.v18.i1.113485

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jan 27, 2026; 18(1): 113485
Published online Jan 27, 2026. doi: 10.4254/wjh.v18.i1.113485

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Figure 3 Immunohistochemical panel of a case of progressive familial intrahepatic cholestasis type 3. A: CK7 immunostain showed ductular reaction and periseptal to panacinar biliary metaplasia (200 ×); B: Bile salt export pump immunostain showed retained canalicular expression (400 ×); C: Multidrug resistance protein 3 immunostain which showed complete loss of canalicular stain (400 ×); D: A case of primary sclerosing cholangitis (control case) showing retained multidrug resistance protein 3 immunostaining (400 ×).

Citation: Thunga C, Mitra S, Babbar A, Lal R, Pal A, Kakkar N, Lal SB. Clinical spectrum and genotype-phenotype correlation of ABCB4 mutations in children: Insights from a North Indian cohort. World J Hepatol 2026; 18(1): 113485
URL: https://www.wjgnet.com/1948-5182/full/v18/i1/113485.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i1.113485

Thunga C, Mitra S, Babbar A, Lal R, Pal A, Kakkar N, Lal SB. Clinical spectrum and genotype-phenotype correlation of ABCB4 mutations in children: Insights from a North Indian cohort. World J Hepatol 2026; 18(1): 113485 [PMID: 41640953 DOI: 10.4254/wjh.v18.i1.113485]

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