Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease

doi:10.4254/wjh.v18.i1.113475

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jan 27, 2026; 18(1): 113475
Published online Jan 27, 2026. doi: 10.4254/wjh.v18.i1.113475

Table 7 Cut-off validation against established thresholds

Marker	Established cut-off	Our cut-off	Clinical utility
FIB-4	> 1.45 (rule-out)	> 1.42	Equivalent rule-out
APRI	> 0.7 (significant)	> 0.68	Validated threshold
PLR	Novel marker	> 142.5	Exploratory
NPAR	Novel marker	> 14.13	Exploratory

FIB-4: Fibrosis index based on four factors; APRI: Aspartate transaminase to platelet ratio index; PLR: Platelet-to-lymphocyte ratio; NPAR: Neutrophil percentage-to-albumin ratio.

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Citation: Joseph A, Mathew S, Nair HR. Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2026; 18(1): 113475
URL: https://www.wjgnet.com/1948-5182/full/v18/i1/113475.htm
DOI: https://dx.doi.org/10.4254/wjh.v18.i1.113475

Joseph A, Mathew S, Nair HR. Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2026; 18(1): 113475 [PMID: 41640950 DOI: 10.4254/wjh.v18.i1.113475]

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