Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease

Table 4 Diagnostic performance of the indices for the differentiation of F3 and F4 from lower stages

Indices	AUC	P value	Sensitivity	Specificity	PPV (%)	NPV (%)	DA (%)
FIB-4	0.806	0.000	0.692	0.804	72.97	77.36	75.63
APRI	0.772	0.000	0.820	0.627	62.75	82.05	71.21
NLR	0.540	0.512	0.462	0.706	54.55	63.16	60.00
PLR	0.301	0.001	0.051	0.980	66.67	57.47	58.43
NPAR	0.673	0.005	0.615	0.745	64.86	71.7	68.88

FIB-4: Fibrosis index based on four factors; APRI: Aspartate transaminase to platelet ratio index; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; NPAR: Neutrophil percentage-to-albumin ratio; AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; DA: Diagnostic accuracy.