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World Journal of Hepatology
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1948-5182
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©The Author(s) 2025.
World J Hepatol. Sep 27, 2025; 17(9): 107671
Published online Sep 27, 2025. doi: 10.4254/wjh.v17.i9.107671
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Figure 3 Hypoxia-induced exosomal release of glypican-3 and its effects on hepatocellular carcinoma progression and angiogenesis. Under hypoxic conditions, hepatocellular carcinoma cells upregulate glypican-3 expression and release it via exosomes, contributing to tumor progression and angiogenesis in the tumor microenvironment. GPC3: Glypican-3; HCC: Hepatocellular carcinoma; EMT: Epithelial-mesenchymal transition.
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