Hepatitis B virus rtCYE/rtCYEI mutations may contribute limited tenofovir resistance: Analysis of a large sample of Chinese patients

doi:10.4254/wjh.v17.i8.107456

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 27, 2025; 17(8): 107456
Published online Aug 27, 2025. doi: 10.4254/wjh.v17.i8.107456

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Figure 2 Assessment of the natural replication capacity of hepatitis B virus. The data are presented as the mean ± SD. Relative replication capacities of rtCYE/rtCYEI-containing mutants and rtWT (laboratory-modified) strain compared to the rtWT strain are presented. ^aP < 0.05 vs rtWT; ^bP < 0.05 vs rtCYE; ^cP < 0.05 vs rtCYEI+M204I. HBV: Hepatitis B virus; rtCYE: rtS106C+H126Y+D134E; rtCYEI: rtS106C+H126Y+D134E+L269I.

Citation: Si LL, Fan ZP, Liu WH, Chen RJ, Chen XY, Ji D, Li L, Chen C, Liao H, Wang J, Xu DP, Zhao J, Liu Y. Hepatitis B virus rtCYE/rtCYEI mutations may contribute limited tenofovir resistance: Analysis of a large sample of Chinese patients. World J Hepatol 2025; 17(8): 107456
URL: https://www.wjgnet.com/1948-5182/full/v17/i8/107456.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i8.107456

Si LL, Fan ZP, Liu WH, Chen RJ, Chen XY, Ji D, Li L, Chen C, Liao H, Wang J, Xu DP, Zhao J, Liu Y. Hepatitis B virus rtCYE/rtCYEI mutations may contribute limited tenofovir resistance: Analysis of a large sample of Chinese patients. World J Hepatol 2025; 17(8): 107456 [PMID: 40901595 DOI: 10.4254/wjh.v17.i8.107456]

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