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©The Author(s) 2025.
World J Hepatol. Aug 27, 2025; 17(8): 107456
Published online Aug 27, 2025. doi: 10.4254/wjh.v17.i8.107456
Published online Aug 27, 2025. doi: 10.4254/wjh.v17.i8.107456
Table 1 Clinical prevalence of rtCYE and rtCYEI mutations in patients infected with different hepatitis B virus genotypes assessed by direct sequencing, n (%)
| Mutation(s) | Genotype A (n = 9) | Genotype B (n = 4266) | Genotype C (n = 23718) | Genotype D (n = 243) |
| rtS106C | 0 (0.00) | 56 (1.31) | 1947 (8.21) | 1 (0.41) |
| rtH126Y | 7 (77.78) | 75 (1.76) | 759 (3.20) | 3 (1.23) |
| rtD134E | 0 (0.00) | 9 (0.21) | 605 (2.55) | 0 (0.00) |
| rtL269I | 2 (22.22) | 3939 (92.33) | 14584 (61.49) | 231 (95.06) |
| rtS106C+H126Y | 0 (0.00) | 0 (0.00) | 114 (0.48) | 0 (0.00) |
| rtS106C+H126Y+D134E | 0 (0.00) | 0 (0.00) | 6 (0.03) | 0 (0.00) |
| rtS106C+H126Y+D134E+L269I | 0 (0.00) | 0 (0.00) | 6 (0.03) | 0 (0.00) |
- Citation: Si LL, Fan ZP, Liu WH, Chen RJ, Chen XY, Ji D, Li L, Chen C, Liao H, Wang J, Xu DP, Zhao J, Liu Y. Hepatitis B virus rtCYE/rtCYEI mutations may contribute limited tenofovir resistance: Analysis of a large sample of Chinese patients. World J Hepatol 2025; 17(8): 107456
- URL: https://www.wjgnet.com/1948-5182/full/v17/i8/107456.htm
- DOI: https://dx.doi.org/10.4254/wjh.v17.i8.107456