Molecular tumor boards in pancreatic cancer with liver metastasis: A case report

Figure 2 Alterations in serum tumor biomarker levels (carbohydrate antigen 19-9, carcinoembryonic antigen, and protein induced by vitamin K absence II) over the course of treatment. A: Carbohydrate antigen 19-9 levels demonstrate a significant therapeutic response with at least 71% reduction from baseline by month 3 (> 120000 U/mL to 34822.9 U/mL), followed by a marked increase beginning at month 12 (8585.77 U/mL; normal range < 37 U/mL); B: The carcinoembryonic antigen level showed a steep decrease spanning month 1 (declining from 527.48 ng/mL to 136.02 ng/mL), at month 13, it began to increase (11.07 ng/mL; normal range ≤ 5 ng/mL); C: The protein induced by vitamin K absence II level exhibited an initial response (baseline 10818 mAU/mL to 56.28 mAU/mL at month 1) preceding a marked rise to 432.81 mAU/mL at month 13 (normal range < 40 mAU/mL). CA199: Carbohydrate antigen 199; CEA: Carcinoembryonic antigen; PIVKA-II: Protein induced by vitamin K absence II.