Role of mac-2 binding protein glycosylation isomer in predicting fibrosis in patients with metabolic dysfunction-associated steatotic liver disease

Table 3 Univariate and multivariate logistic regression identification of risk factors of significant fibrosis and cirrhosis, n (%)

Condition	Variable	Univariate analysis		Multivariate analysis
		OR	95%CI	Adjusted OR	95%CI
Significant fibrosis	Age	1.02	1-1.04	1	0.98-1.03
	Sex
	Male	Reference		Reference
	Female	1.15	0.69-1.91	0.72	0.4-1.3
	FIB-4	2.41	1.48-4.23	2.1	1.18-4.3
	M2BPGi (COI)	2.3	1.18-4.93	1.6	0.74-3.8
	HbA1c	1.43	1.13-1.86	1.4	1.08-1.81
Cirrhosis	Age	1	0.98-1.03	0.99	0.96-1.03
	Sex
	Male	1.5	0.79-3.13	2.5	1.1-5.78
	Female	Reference		Reference
	FIB-4	2.2	1.54-3.35	1.2	0.92-1.53
	M2BPGi (COI)	2.4	1.37-4.47	1.7	0.85-3.6
	HbA1c	1.2	0.95-1.45	1.2	0.92-1.53

COI: Cut-off index; FIB-4: Fibrosis-4 Index; HbA1c: Hemoglobin A1c; M2BPGi: Mac-2 binding protein glycosylation isomer; OR: Odds ratio.