Sex-related differences in patients with chronic hepatitis C infection treated with direct-acting antiviral drugs

doi:10.4254/wjh.v17.i6.105899

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Jun 27, 2025 (publication date) through Jul 25, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jun 27, 2025; 17(6): 105899
Published online Jun 27, 2025. doi: 10.4254/wjh.v17.i6.105899

Table 2 Comparison of treatment characteristics of women and men depending on age, n (%)

Parameter	Women 15-44 years, n = 3118	Men 15-44 years, n = 4163	P value	Women 45-55 years, n = 1689	Men 45-55 years, n = 2185	P value	Women > 55 years, n = 4650	Men > 55 years, n = 3181	P value
History of previous therapy			0.001			0.0006			0.06
Treatment-naïve	2748 (88.13)	3550 (85.28)		1399 (82.83)	1704 (77.99)		3572 (76.86)	2369 (74.5)
Treatment-experienced	370 (11.87)	613 (14.72)		290 (17.17)	481 (22.01)		1076 (23.14)	811 (25.5)
Current regimen			< 0.001			0.0004			0.02
Genotype-specific	1573 (50.45)	1817 (43.65)		823 (48.73)	930 (42.56)		2872 (61.76)	1869 (58.76)
Pangenotypic	1545 (49.55)	2346 (56.35)		866 (51.27)	1255 (57.44)		1778 (38.24)	1312 (41.24)

Citation: Dobrowolska K, Zarębska-Michaluk D, Pawłowska M, Tudrujek-Zdunek M, Lorenc B, Berak H, Janczewska E, Mazur W, Janocha-Litwin J, Klapaczyński J, Sitko M, Dybowska D, Parfieniuk-Kowerda A, Piekarska A, Jaroszewicz J, Flisiak R. Sex-related differences in patients with chronic hepatitis C infection treated with direct-acting antiviral drugs. World J Hepatol 2025; 17(6): 105899
URL: https://www.wjgnet.com/1948-5182/full/v17/i6/105899.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i6.105899