Machine learning to identify potential biomarkers for sarcopenia in liver cirrhosis

Table 1 Demographic and clinical variables of the subjects, n (%)

	Cirrhosis with sarcopenia (n = 41)	Cirrhosis without sarcopenia (n = 21)	P value
Gender			< 0.001
Male	15 (36.6)	19 (90.5)
Female	26 (63.4)	2 (9.5)
Age (years)	58 (53.5, 63.5)	50 (48, 56)	0.002
Body mass index (kg/m2)	20.98 (19.06, 24.13)	24.22 (23.03, 25.95)	0.002
Child-Pugh
A	9 (22)	12 (57.1)	0.005
B	10 (24.4)	6 (28.6)
C	22 (53.7)	3 (14.3)
Duration of cirrhosis			0.353
< 5 years	21 (51.2)	12 (57.2)
5-10 years	10 (24.4)	7 (33.3)
> 10 years	10 (24.4)	2 (9.5)
Alanine aminotransferase (U/L)	22.04 (16.48, 37.47)	29.1 (16.59, 45.79)	0.661
Aspartate aminotransferase (U/L)	36.69 (27.64, 44.94)	37.94 (26.34, 44.92)	0.953
Albumin (g/L)	33.51 (27.34, 35.88)	34.71 (28.1, 38.07)	0.557
Total protein (g/L)	66.64 (63.37, 71.65)	66.36 (62.34, 69.01)	0.475
Total bilirubin (mmol/L)	22.79 (16.5, 34.85)	32.64 (19.26, 43.5)	0.356
Urea (mmol/L)	5.14 ± 2.56	5.14 ± 2.11	0.996
Creatinine (μmol/L)	58.12 ± 13.99	68.67 ± 17.66	0.013
Ammonia (μmol/L)	33.92 ± 7.76	36.24 ± 9.03	0.298
Serum ferritin (μg/L)	38.27 ± 38.23	85.92 ± 77.67	0.014
Prothrombin time (second)	14.2 (13.3, 15.5)	14.8 (13.75, 17.75)	0.054