Trends in viral hepatitis-related mortality in the United States from 1999 to 2022: A retrospective study

Table 4 Viral hepatitis annual percent change and average annual percent change in the age-adjusted mortality rate per 100000 people; stratified by race, 1999-2022

Cohort	Statistic	Segment	Years	Percent change	95%CI	P value
American Indian or Alaska Native	APC	1	1999-2012	5.91	(4.66, 7.95)	P < 0.001
		2	2012-2022	-0.88	(-2.61, 0.53)
	AAPC	Full range	1999-2022	2.90	(2.30, 3.68)	P < 0.001
Asian or Pacific Islander	APC	1	1999-2011	0.13	(-1.24, 2.77)
		2	2011-2022	-5.05	(-7.09, -3.76)	P < 0.001
	AAPC	Full range	1999-2022	-2.39	(-3.04, -1.57)	P < 0.001
Black or African American	APC	1	1999-2014	2.23	(1.78, 2.71)	P < 0.001
		2	2014-2022	-6.54	(-7.56, -5.53)	P < 0.001
	AAPC	Full range	1999-2022	-0.91	(-1.18, -0.63)	P < 0.001
White	APC	1	1999-2007	4.52	(3.68, 7.01)	P < 0.001
		2	2007-2014	2.20	(-0.87, 3.06)
		3	2014-2022	-5.31	(-6.26, -4.51)	P < 0.001
	AAPC	Full range	1999-2022	0.30	(0.05, 0.61)	P < 0.05
Hispanic or Latino	APC	1	1999-2013	1.35	(0.61, 2.20)	P < 0.001
		2	2013-2022	-8.48	(-9.79, -7.29)	P < 0.001
	AAPC	Full range	1999-2022	-2.62	(-3.04, -2.20)	P < 0.001

APC: Annual percentage change; AAPC: Average annual percentage change.