Trends in viral hepatitis-related mortality in the United States from 1999 to 2022: A retrospective study

doi:10.4254/wjh.v17.i5.106940

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May 27, 2025 (publication date) through May 30, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Hepatol. May 27, 2025; 17(5): 106940
Published online May 27, 2025. doi: 10.4254/wjh.v17.i5.106940

Table 10 Viral hepatitis annual percent change and average annual percent change in the age-adjusted mortality rate per 100000 people; stratified by urban vs rural, 1999-2022

Cohort	Statistic	Segment	Years	Percent change	95%CI	P value
Urban	APC	1	1999-2013	2.98	(2.28, 3.80)	P < 0.001
		2	2013-2022	-6.13	(-7.97, -4.62)	P < 0.001
	AAPC	Full range	1999-2022	-0.15	(-0.59, 0.29)
Rural	APC	1	1999-2002	10.66	(5.48, 19.12)	P < 0.001
		2	2002-2014	4.05	(2.19, 4.67)	P < 0.05
		3	2014-2022	-3.60	(-5.44, -2.14)	P < 0.05
	AAPC	Full range	1999-2022	2.71	(2.22, 3.29)	P <0.001

APC: Annual percentage change; AAPC: Average annual percentage change.

Citation: Ahlers L, Kash B, Billion T, Mirza M, Tauseef A. Trends in viral hepatitis-related mortality in the United States from 1999 to 2022: A retrospective study. World J Hepatol 2025; 17(5): 106940
URL: https://www.wjgnet.com/1948-5182/full/v17/i5/106940.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i5.106940