Modern ultrasound techniques for diagnosing liver steatosis and fibrosis: A systematic review with a focus on biopsy comparison

Table 7 Transient elastography diagnostic efficacy (area under the receiver operating characteristic curves for fibrosis detection)

Ref.	Number of patients	Disease/diagnose	Diagnostic method	Fibrosis stage	AUROC (CI)	Assessment
Mendoza et al[34]	200	NAFLD	TE	≥ F2	0.76 (0.64-0.88)	Acceptable
				≥ F3	0.72 (0.63-0.82)	Acceptable
				F4	0.89 (0.78-1.00)	Good
Patidar et al[39]	127	Diffuse liver diseases	TE	F0-F1	0.824 (0.72-1)	Good
				F1-F2	0.935 (0.906-1)	Good
				F2-F3	0.964 (0.883-1)	Good
				F3-F4	0.979 (0.633-1)	Good
Seyrek et al[42]	146	CLD	TE	> F2	0.79 (0.65-0.94)	Acceptable
Taibbi et al[46]	56	NAFLD	TE	F2-F4	0.719 (0.572-0.867)	Acceptable
				F3-F4	0.799 (0.646-0.952)	Acceptable
Yoo et al[52]	115	CLD	TE	F2	0.859 (0.781-0.916)	Good
				F3	0.881 (0.807-0.934)	Good
				F4	0.938 (0.877-0.974)	Excellent
Kim et al[67]	60	NASH	TE	≥ F1	0.733 (0.603-0.839)	Acceptable
				≥ F2	0.828 (0.709-0.913)	Good
				≥ F3	0.869 (0.756-0.942)	Good
				≥ F4	0.891 (0.783-0.957)	Good

AUROC: Area under the receiver operating characteristic curve; NAFLD: Nonalcoholic fatty liver disease; CLD: Chronic liver disease; SWE: Shear wave elastography; TE: Transient elastography; NASH: Nonalcoholic steatohepatitis.