Modern ultrasound techniques for diagnosing liver steatosis and fibrosis: A systematic review with a focus on biopsy comparison

Table 10 Diagnostic efficacy of sound touch elastography and related techniques (area under the receiver operating characteristic curves for fibrosis detection)

Ref.	Number of patients	Disease/diagnose	Diagnostic method	Fibrosis stage	AUROC (CI)	Assessment
Gatos et al[27]	152	CLD	ViTE	F ≥ F1	0.9481	Excellent
				F ≥ F2	0.9698	Excellent
				F ≥ F3	0.9846	Excellent
				F = F4	0.9524	Excellent
Yang et al[50]	106	CLD	ViTE	F0 vs F1-3	0.88	Good
				F0-1 vs F2-4	0.84	Good
				F0-2 vs F3-4	0.80	Acceptable
				F0-3 vs F4	0.80	Acceptable
Yu et al[62]	85	T2DM	FibroTouch	≥ F2	0.76 (0.66-0.86)	Acceptable
				≥ F3	0.81 (0.71-0.91)	Good
				≥ F4	0.92 (0.85-1.00	Excellent
Qu et al[60]	237	NAFLD	FibroTouch	≥ F2	0.71	Acceptable
				≥ F3	0.71	Acceptable
				F4	0.77	Acceptable

AUROC: Area under the receiver operating characteristic curve; CLD: Chronic liver disease; ViTE: Visual transient elastography; NAFLD: Nonalcoholic fatty liver disease; T2DM: Type 2 diabetes mellitus.