Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers

Figure 4 Volcano plots showing differentially expressed genes in the comparison of non-stimulated and fecal extracts-stimulated peripheral blood mononuclear cells isolated from patients with non-alcoholic fatty liver disease patients and controls. A and B: Patients with non-alcoholic fatty liver disease. Genes highlighted based on statistical significance (lowest adjusted P-values) (A), genes highlighted based on fold change (top upregulated and downregulated genes) (B); C and D: Control group. Genes highlighted based on statistical significance (lowest adjusted P-values) (C), fecal extracts-stimulated peripheral blood mononuclear cells: Genes highlighted based on fold change (top upregulated and downregulated genes) (D).