Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers

doi:10.4254/wjh.v17.i12.113359

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Dec 27, 2025; 17(12): 113359
Published online Dec 27, 2025. doi: 10.4254/wjh.v17.i12.113359

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Figure 1 Principal component analysis comparing the transcriptome profiles of peripheral blood mononuclear cells isolated from patients with non-alcoholic fatty liver disease patients and controls. A: Non-stimulated; B: Fecal extract-stimulated. PBMCs: Peripheral blood mononuclear cells; FEs: Fecal extracts; PC: Principal component; NAFLD: Non-alcoholic fatty liver disease.

Citation: Zeber-Lubecka N, Michalkiewicz J, Dabrowska M, Goryca K, Wierzbicka-Rucińska A, Jańczyk W, Jankowska I, Świąder-Leśniak A, Kubiszewska I, Ziemska-Legięcka J, Socha P, Ostrowski J. Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers. World J Hepatol 2025; 17(12): 113359
URL: https://www.wjgnet.com/1948-5182/full/v17/i12/113359.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i12.113359

Zeber-Lubecka N, Michalkiewicz J, Dabrowska M, Goryca K, Wierzbicka-Rucińska A, Jańczyk W, Jankowska I, Świąder-Leśniak A, Kubiszewska I, Ziemska-Legięcka J, Socha P, Ostrowski J. Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers. World J Hepatol 2025; 17(12): 113359 [PMID: 41479518 DOI: 10.4254/wjh.v17.i12.113359]

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