He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation in vivo and in vitro

doi:10.4254/wjh.v17.i12.112835

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Dec 27, 2025; 17(12): 112835
Published online Dec 27, 2025. doi: 10.4254/wjh.v17.i12.112835

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Figure 3 He-He-Shu-Yang formula inhibits hepatic stellate cell activation in rats with carbon tetrachloride-induced fibrosis. ^bP < 0.01 vs control group; ^dP < 0.01 vs model group. A: Representative images of α-smooth muscle actin immunohistochemical staining in the indicated treatment groups (bar = 50 μm); B: Average optical density of α-smooth muscle actin in each group. HSC: Hepatic stellate cell; α-SMA: Α-smooth muscle actin; HHSY: He-He-Shu-Yang formula; AOD: Average optical density; A.U.: Arbitrary unit.

Citation: Zeng FL, Shi MJ, Mo YS, Xiao HM, Xie YB, Chi XL. He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation in vivo and in vitro. World J Hepatol 2025; 17(12): 112835
URL: https://www.wjgnet.com/1948-5182/full/v17/i12/112835.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i12.112835

Zeng FL, Shi MJ, Mo YS, Xiao HM, Xie YB, Chi XL. He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation in vivo and in vitro. World J Hepatol 2025; 17(12): 112835 [PMID: 41479505 DOI: 10.4254/wjh.v17.i12.112835]

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