Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease

Figure 1 Illustration of signal intensity measurement methodology on axial T1-weighted volumetric interpolated breath-hold examination images with fat suppression, acquired during the native and hepatobiliary phases. A and B: The native phases; C and D: The hepatobiliary phases. Images A and C depict signal intensity measurements in segment III, whereas images B and D demonstrate the same technique applied to segment VIII. Orange circles represent four manually positioned circular regions of interest, each spanning 1 cm², situated within homogeneous liver parenchyma. The regions of interest were consistently replicated in identical locations across the two phases to ensure precise and comparable signal intensity evaluation.