Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease

doi:10.4254/wjh.v17.i12.111418

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Hepatol. Dec 27, 2025; 17(12): 111418
Published online Dec 27, 2025. doi: 10.4254/wjh.v17.i12.111418

Table 3 Correlations among hepatobiliary signal intensity, Functional Liver Imaging Score, clinical scores, liver stiffness, and hepatic venous-portal gradient

Region	FLIS	Child-Pugh	MELD 3.0	ALBI	FIB-4	Liver stiffness	HVPG
SI segment III	0.661^a	-0.496^a	-0.521^a	-0.519^a	-0.222^a	-0.389^a	-0.167 (P = 0.208)
SI segment VI	0.763^a	-0.589^a	-0.623^a	-0.603^a	-0.268^a	-0.390^a	-0.267 (P = 0.094)
SI segment VIII	0.683^a	-0.463^a	-0.545^a	-0.493^a	-0.259^a	-0.422^a	-0.302 (P = 0.067)
SI caudate lobe	0.727^a	-0.532^a	-0.563^a	-0.562^a	-0.266^a	-0.461^a	-0.289 (P = 0.076)
Global SI	0.736^a	-0.540^a	-0.584^a	-0.565^a	-0.263^a	-0.429^a	-0.261 (P = 0.099)

^aP < 0.05.

ALBI: Albumin-bilirubin score; FIB-4: Fibrosis-4 index; FLIS: Functional Liver Imaging Score; HVPG: Hepatic venous-portal gradient; MELD: Model for End-Stage Liver Disease; SI: Signal intensity.

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Citation: Stanciu BI, Iojiban M, Morariu-Barb A, Caraiani C, Procopet B, Stefanescu H, Lupsor-Platon M. Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease. World J Hepatol 2025; 17(12): 111418
URL: https://www.wjgnet.com/1948-5182/full/v17/i12/111418.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i12.111418

Stanciu BI, Iojiban M, Morariu-Barb A, Caraiani C, Procopet B, Stefanescu H, Lupsor-Platon M. Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease. World J Hepatol 2025; 17(12): 111418 [PMID: 41479507 DOI: 10.4254/wjh.v17.i12.111418]

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