Roles of short-chain fatty acids in metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis

Figure 1 Short-chain fatty acids produced by gut microbiota and up taken by the liver. Dietary fiber or probiotics are fermented by gut microbiota to produce short-chain fatty acids (SCFAs). SCFAs mediate intestinal cell mitochondrial energy production. SCFAs are taken up by the liver through portal circulation and enter systemic circulation. SCFAs: Short-chain fatty acids; ATP: Adenosine triphosphate. This figure was created using BioRender.com (Supplementary material).