Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Nov 27, 2025; 17(11): 111576
Published online Nov 27, 2025. doi: 10.4254/wjh.v17.i11.111576

Table 2 Ethnic predominance of major genes involved in metabolic dysfunction-associated steatotic liver disease

Gene	Ethnic predominance
PNLPA3	Hispanics, Asians
TM6SF2	Caucasians and African Americans
GCKR	European Americans and Middle East
HSD17B13	Europeans

Citation: Kumar G, Shah YR, Shahzad A, Jameel K, Guevara-Lazo D, Khan NA, Dahiya DS, Gangwani MK, Ravichandran R, Patel R, Hayat U, Thandassery RB. Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology. World J Hepatol 2025; 17(11): 111576
URL: https://www.wjgnet.com/1948-5182/full/v17/i11/111576.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i11.111576

Kumar G, Shah YR, Shahzad A, Jameel K, Guevara-Lazo D, Khan NA, Dahiya DS, Gangwani MK, Ravichandran R, Patel R, Hayat U, Thandassery RB. Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology. World J Hepatol 2025; 17(11): 111576 [PMID: 41368108 DOI: 10.4254/wjh.v17.i11.111576]

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