Direct-acting antiviral therapy reduces variceal rebleeding and improves liver function in hepatitis C virus-related cirrhosis: A multicenter retrospective cohort study

Table 12 Machine learning predictors of variceal rebleeding

Variable	Importance Score	P value	AUC (95%CI)
DAA treatment	0.85	< 0.001a	0.82 (0.76-0.88)
MELD score	0.78	< 0.001a
Platelets (< 150 × 10³/μL)	0.72	< 0.001a
Child-Pugh class B	0.68	0.001a

^aP < 0.05.

Importance scores were derived from random forest and LASSO regression models. area under the curve for the final model: 0.82 (95%CI: 0.76-0.88). AUC: Area under the curve; MELD: Model for end-stage liver disease; DAA: Direct-acting antiviral.