Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges

doi:10.4254/wjh.v17.i11.110614

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Nov 27, 2025; 17(11): 110614
Published online Nov 27, 2025. doi: 10.4254/wjh.v17.i11.110614

Table 4 A comparison between transarterial chemoembolization and transarterial radioembolization

Therapy	Vp2 PVTT	Vp3 PVTT	ORR (%)	Median OS (months)	Safety profile
TACE	Moderate	Moderate	50-70	18-24	Moderate
TARE	High	Moderate	60-80	22-30	Low

TACE: Transarterial chemoembolization; TARE: Transarterial radioembolization; PVTT: Portal vein tumor thrombus; ORR: Objective response rate; OS: Overall survival.

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Citation: Li ZY, Xie C, Cai HQ. Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges. World J Hepatol 2025; 17(11): 110614
URL: https://www.wjgnet.com/1948-5182/full/v17/i11/110614.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i11.110614

Li ZY, Xie C, Cai HQ. Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges. World J Hepatol 2025; 17(11): 110614 [PMID: 41376836 DOI: 10.4254/wjh.v17.i11.110614]

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