Laparoscopic vs open surgery for complex hepatolithiasis: A retrospective comparative study

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Hepatol. Nov 27, 2025; 17(11): 110050
Published online Nov 27, 2025. doi: 10.4254/wjh.v17.i11.110050

Table 1 Baseline demographic and clinical characteristics of patients undergoing laparoscopic vs open surgery for complex hepatolithiasis, n (%)

Variable	Laparoscopic group (n = 40)	Open surgery group (n = 40)	χ²/t/Mann-Whitney U test	P value
Age (years, mean ± SD), (range)	52.7 ± 12.1 (23.0-81.0)	56.1 ± 12.9 (34.0-80.0)	-1.215	0.228
Sex
Female	24 (60.0)	26 (65.0)	0.213	0.644
Male	16 (40.0)	14 (35.0)	-	-
BMI (kg/m², IQR)	20.0 (18.0-21.0)	20.0 (19.0-22.5)	-0.998	0.318
Hepatitis B	8 (20.0)	7 (17.5)	0.082	0.775
Malnutrition	6 (15.0)	8 (20.0)	0.346	0.556
Diabetes	6 (15.0)	7 (17.5)	0.092	0.762
Presentation
Acute cholangitis	37 (92.5)	36 (90.0)	-	1.000¹
Acute pancreatitis	9 (22.5)	8 (20.0)	0.075	0.785
Liver abscess	12 (30.0)	15 (37.5)	0.503	0.478
Lung abscess	2 (5.0)	1 (2.5)	-	1.000¹
Previous operation
Cholecystectomy	34 (85.0)	35 (87.5)	0.105	0.745
Bilioenteric anastomosis	7 (17.5)	7 (17.5)	0.000	1.000
Exploration of bile duct	35(87.5)	33 (82.5)	0.392	0.531
Hepatectomy	10 (25.0)	11 (27.5)	0.065	0.799
Concomitant condition
Gallbladder stones	3 (7.5)	4 (10.0)	-	1.000¹
Extrahepatic biliary stones	34 (85.0)	33 (82.5)	0.092	0.762
Hepatic atrophy	12 (30.0)	15 (37.5)	0.503	0.478
Cirrhosis	6 (15.0)	7 (17.5)	0.092	0.762
Intrahepatic biliary stricture	38 (95.0)	38 (95.0)	-	1.000¹

¹Fisher’s exact test.

BMI: Body mass index; IQR: Interquartile range.

Citation: Lin DX, Zhuo XB, Chang GJ, Lei WD, Huang J, Zhang Y, Qiu ZJ, Zhang SY. Laparoscopic vs open surgery for complex hepatolithiasis: A retrospective comparative study. World J Hepatol 2025; 17(11): 110050
URL: https://www.wjgnet.com/1948-5182/full/v17/i11/110050.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i11.110050

Lin DX, Zhuo XB, Chang GJ, Lei WD, Huang J, Zhang Y, Qiu ZJ, Zhang SY. Laparoscopic vs open surgery for complex hepatolithiasis: A retrospective comparative study. World J Hepatol 2025; 17(11): 110050 [PMID: 41368111 DOI: 10.4254/wjh.v17.i11.110050]

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