Clinical significance and pathogenic mechanisms of fatigue in metabolic dysfunction-associated steatotic liver disease

doi:10.4254/wjh.v17.i10.110848

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 27, 2025; 17(10): 110848
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.110848

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Figure 1 Differentiating fatigue from depression: Major symptoms, commonly used diagnostic tools, and key pathogenic mechanisms. EQ-5D: European Quality of Life 5-Dimension 5-Level Questionnaire; HPA: Hypothalamic-pituitary-adrenal; CLD: Chronic liver disease; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; CRP: C-reactive protein.

Citation: Sheptulina AF, Golubeva JA, Kiselev AR, Drapkina OM. Clinical significance and pathogenic mechanisms of fatigue in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2025; 17(10): 110848
URL: https://www.wjgnet.com/1948-5182/full/v17/i10/110848.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i10.110848

Sheptulina AF, Golubeva JA, Kiselev AR, Drapkina OM. Clinical significance and pathogenic mechanisms of fatigue in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2025; 17(10): 110848 [PMID: 41179723 DOI: 10.4254/wjh.v17.i10.110848]

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