©The Author(s) 2025.
World J Hepatol. Oct 27, 2025; 17(10): 108810
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.108810
Published online Oct 27, 2025. doi: 10.4254/wjh.v17.i10.108810
Figure 3 Schematic representation of therapeutic strategies for liver fibrosis.
Nanoparticles, microbubbles paired with ultrasound, or a mix of the two can be used to deliver drug-based and gene-based therapies. Microbubble oscillation transiently disrupts endothelial and extracellular matrix barriers, enhancing nanoparticle uptake. These delivery systems aim to improve tissue penetration and therapeutic efficacy.
- Citation: Armillotta MG, Lizzi L, Massimi M. Nanoparticle-based systems for liver therapy: Overcoming fibrosis and enhancing drug efficacy. World J Hepatol 2025; 17(10): 108810
- URL: https://www.wjgnet.com/1948-5182/full/v17/i10/108810.htm
- DOI: https://dx.doi.org/10.4254/wjh.v17.i10.108810