Effect of alpha-lipoic acid and Silybum marianum supplementation with a Mediterranean diet on metabolic dysfunction-associated steatosis

Table 2 Somatometric characteristics at baseline and at weeks 12 and 24 in the intervention group with metabolic dysfunction-associated steatotic liver disease

SM-ALA + MD	Baseline	12 weeks	24 weeks	P value
Somatometry
Weight in kg	82.2 + 16.4	80.1 + 16.2	78.8 + 16.7	0.393
∆weight	-	-1.7 + 2.9	-2.5 + 3.5	0.388
BMI	32.8 + 6.9	32.5 + 6.8	32.4 + 7.05	0.57
Visceral fat as %	12.4 + 3.4	11.9 + 3.3	11.5 + 3.5	0.045
∆visceral fat	-	-0.54 + 1.6	-0.95 + 2.1	0.268
Total fat as %	41.9 + 10.8	42.0 + 10.5	41.0 + 11.5	0.744
Muscle as %	25.5 + 5.4	26.5 + 22.5	26.6 + 8.6	0.554
Circumference in cm
Umbilical	101.8 + 14.7	95.4 + 22.5	97.4 + 14.5	0.003
Hip	112.8 + 16.2	110.2 + 14.0	109.9 + 14.4	0.248
Waist	99.9 + 15.2	96.3 + 13.4	95.9 + 15.0	0.117
Waist-to-hip ratio	0.88 + 0.8	0.87 + 0.06	0.87 + 0.06	0.206
Elastography
kPa1	6.2 + 2.6	5.9 + 2.3	5.4 + 2.03	0.083
∆kPa	-	-0.29 + 2.9	-0.71 + 1.89	0.33

¹Non-normal distribution. ALA: Alpha-lipoic acid; BMI: Body mass index; MD: Mediterranean diet; SM: Silybum marianum.