Gadoxetic acid-enhanced magnetic resonance imaging in the assessment of hepatic sinusoidal obstruction syndrome in a mouse model

Table 1 Histological features in sinusoidal obstruction syndrome

No.	Central vein endothelial damage	Central vein subendothelial hemorrhage	Sinusoidal hemorrhage	Lobular inflammation	Hepatocyte necrosis	Centrilobular fibrosis	All scores
1	2	1	2	1	0	0	6
2	0	1	1	0	0	0	2
3	1	1	1	1	0	0	4
4	1	1	1	0	0	0	3
5	0	1	1	0	0	2	2
6	1	0	0	1	0	0	2
7	1	0	0	0	0	0	1
8	1	1	0	1	1	1	5
9	1	1	1	1	0	1	5
10	2	2	1	1	1	1	8
11	1	2	1	1	0	1	6
12	1	2	2	1	1	1	8
13	2	3	3	3	0	0	11

Each pathological feature was assessed using a 4-point grading system: 0 = absent; 1 = mild; 2 = moderate; 3 = severe. All score = total scores of the six pathological features.