Molecular mechanism of nanomaterials induced liver injury: A review

Table 14 Effects and molecular mechanisms underlying cobalt NPs induced hepatonanotoxicity

NPs	Size	Tested model	Dose & route of administration	Effects & mechanism	Ref.
Nano-Co	10-40 nm	Normal human liver L02 cells	2.5, 5, 7.5, 10, 20, and 40 μg/mL) for 12 h or 24 h	Modulation of ROS/NLRP3 pathway	[162]

NLRP3: NOD-like receptor protein 3; ROS: Reactive oxygen species.