Quantitative hepatitis B core antibody and quantitative hepatitis B surface antigen: Novel viral biomarkers for chronic hepatitis B management

doi:10.4254/wjh.v16.i4.550

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Apr 27, 2024 (publication date) through May 19, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Apr 27, 2024; 16(4): 550-565
Published online Apr 27, 2024. doi: 10.4254/wjh.v16.i4.550

Table 3 Summary of the characteristics of quantitative hepatitis B antibody assays from several companies

Test names	Companies	Principle techniques	Detection methods	Range of detection
Anti-HBc QN[93]	Wantai BioPharm	Double-antigen sandwich	ELISA	0.1–25 IU/mL
Anti-HBc HQ[94]	United Medical Instruments	Fully automated two-step sandwich	CMIA	100–100000 IU/mL
Lumipulse G HBcAb-N[95]	Fujirebio Incorporation	Fully automated two-step sandwich	CLEIA	0.5–50 IU/mL
Europium III chelate microparticles HBcAb[96]	Guangzhou Darui Biotechnology	Rapid fluorescence POCT	LFIA	0-640 IU/mL

CLEIA: Chemiluminescent enzyme immunoassay; CMIA: Chemiluminescent microparticle immunoassay; ELISA: Enzyme-linked immunosorbent assay; HBcAb: Hepatitis B core antibody; HQ: High value quantitative detection; LFIA: Lateral flow immunoassay; POCT: Point-of-care test; QN: General value quantitative detection.

Citation: Leowattana W, Leowattana P, Leowattana T. Quantitative hepatitis B core antibody and quantitative hepatitis B surface antigen: Novel viral biomarkers for chronic hepatitis B management. World J Hepatol 2024; 16(4): 550-565
URL: https://www.wjgnet.com/1948-5182/full/v16/i4/550.htm
DOI: https://dx.doi.org/10.4254/wjh.v16.i4.550