Prediction model for hepatitis B e antigen seroconversion in chronic hepatitis B with peginterferon-alfa treated based on a response-guided therapy strategy

Table 2 Selected variables by multivariate analysis at baseline, week 12, and week 24 to construct predictive models for response at 24 wk post-treatment

	Selected predictive variables	Multivariate analysis OR (95%CI)	P value
Baseline	HBsAg ≤ 1000 IU/mL	0.466 (0.153-1.421)	0.180
	HBeAg ≤ 3 S/CO	0.222 (0.074-0.671)	0.008
12 wk	HBsAg ≤ 600 IU/mL	0.271 (0.091-0.810)	0.019
	HBeAg ≤ 3 S/CO	0.230 (0.079-0.668)	0.007
24 wk	HBsAg ≤ 300 IU/mL	0.225 (0.067-0.759)	0.016
	HBeAg ≤ 2 S/CO	0.089 (0.027-0.297)	< 0.001

HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; OR: Odds ratio; CI: Confidence interval.