Comparison of fungal vs bacterial infections in the medical intensive liver unit: Cause or corollary for high mortality?

Table 4 Comparison of infection characteristics among liver patients in intensive care unit between fungal and bacterial cohorts

Characteristic	Bacteria, n = 1831	Fungal, n = 271	P value2
MDRO	90 (50)	10 (37)	0.2
MELD-Na (time of positive culture)	28 (22, 33)	33 (25, 38)	0.017
Child-Pugh score (time of positive culture)	11.00 (9.00, 12.00)	11.00 (10.00, 13.00)	0.064
CLIF-C score (time of positive culture)	11.00 (9.00, 13.00)	13.00 (12.00, 14.50)	< 0.001
Lab values of interest at time of culture
Leukocyte count	13 (7, 19)	16 (11, 18)	> 0.9
C-reactive protein	6 (3, 12)	5 (4, 8)	0.057
Albumin	2.70 (2.20, 3.30)	3.10 (2.70, 3.40)	0.086
Bilirubin	6 (2, 13)	13 (4, 23)	0.035
Lactate	2.9 (1.9, 5.2)	4.4 (2.2, 7.3)	0.3
International normalized ratio	1.80 (1.40, 2.10)	2.05 (1.78, 3.00)	0.046

¹n (%); Median (IQR).

²Pearson's Chi-squared test; Wilcoxon rank sum test; Fisher's exact test; Welch Two Sample test.

MDRO: Multi-drug resistant organism; MELD-Na: Model for End Stage Liver Disease-Sodium; CLIF: Chronic liver failure consortium organ failure score.