Comparison of fungal vs bacterial infections in the medical intensive liver unit: Cause or corollary for high mortality?

Table 3 Transplant and intensive care outcomes comparison between fungal and bacterial cohorts

Characteristic	Bacteria, n = 1831	Fungal, n = 271	P value2
Intensive care outcomes
ACLF grade			0.017
< 2	50 (36)	2 (9.5)
≥ 2	90 (64)	19 (90)
Death during admission or hospice	95 (52)	25 (93)	< 0.001
Vasopressor requirement	129 (70)	26 (96)	0.004
Mechanical ventilation	118 (65)	26 (96)	< 0.001
Indication for intubation
Airway protection	93 (79)	22 (85)	0.6
Respiratory failure	25 (21)	4 (15)
Dialysis due to acute kidney injury	95 (52)	21 (78)	0.014
ICU LOS (d)	5 (2, 10)	6 (4, 16)	0.063
Hospital LOS (d)	16 (7, 28)	17 (12, 30)	0.3
Hosp admit to ICU (d)	0 (0, 6)	8 (0, 13)	0.046
Transplant-related outcomes
Evaluated for transplant	107 (58)	13 (48)	0.3
Listed	57 (53)	4 (31)	0.13
Organ listed			0.3
Liver	44 (79)	3 (60)
Liver and kidney	12 (21)	2 (40)
Hold placed	32 (57)	4 (100)	0.14
Transplant occurred	28 (50)	0 (0)	0.056

¹n (%); Range; Median (IQR).

²Pearson's Chi-squared test; Wilcoxon rank sum test; Fisher's exact test.

ACLF: Acute on chronic liver failure; ICU: Intensive care unit; LOS: Length of stay.